5/18/2023 0 Comments Pituitary adrenal glandsHowever, undoubtedly, it represents a new intriguing field of science research.Įndocrine disrupting chemicals (EDCs) are defined as “exogenous chemicals or mixture of chemicals that interfere with any aspect of hormone action”. ConclusionsĪlthough intriguing, studies on endocrine dysfunctions brought by EDCs are challenging, in particular when investigating long-term effects of EDCs on humans. We also gave a glimpse on recent findings from pioneering studies that could in the future shed a light on the pathophysiology of well-known, but poorly understood, endocrine diseases like hormone-producing adenomas. Particularly, we directed our attention on the known and the hypothesized mechanisms of endocrine dysfunction brought by EDCs. This paper aims to summarize current evidence regarding the detrimental effects of EDCs on pivotal endocrine glands like pituitary, thyroid and adrenal ones. As a result, we witnessed a growing awareness and interest on this topic. This induced regulatory authorities to ban some of these compounds and to carefully investigate others in order to prevent EDCs-related conditions. In recent years, scientific research has increasingly focused on Endocrine Disrupting Chemicals (EDCs) and demonstrated their relevant role in the functional impairment of endocrine glands.
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